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3state_with_SRX

This scheme is similar to that described in PMC6084639. See the publication for additional details.

See ramp_3 for an example simulation using this scheme.

Myosin heads transition between an OFF, an ON, and a force-generating state. Binding sites on actin switch between states that are unavailable and available for myosin heads to attach to.

kinetic_scheme

The fluxes are as defined in PMC6084639 except that

J4 = k_4_0 + (k_4_1 * x4)

The model parameters that need to be defined in the model file file are:

  • k_1
  • k_force
  • k_2
  • k_3
  • k_4_0
  • k_4_1
  • k_on
  • k_off
  • k_coop