3state_with_SRX_and_exp_k4

This scheme is a modification of that described in PMC6084639. See the publication for additional details.

See twitch_1 for an example simulation using this scheme.

Myosin heads transition between an OFF, an ON, and a force-generating state. Binding sites on actin switch between states that are unavailable and available for myosin heads to attach to.

kinetic_scheme

The fluxes are as defined in PMC6084639 except that

J4 = k_4_0 * exp(-k_4_1 * x)

The model parameters that need to be defined in the model file file are:

k_1
k_force
k_2
k_3
k_4_0
k_4_1
k_on
k_off
k_coop